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Clinical Specialists

Heart rhythm trends even in normal ranges provide insights to treatment sequencing and adverse event patterns in specific disease and drug combinations.

Monitoring across specialties with cardiac risks

BiosignalsDx services are initiated by Specialists across multiple clinical sectors where longitudinal cardiac monitoring closes a meaningful diagnostic gap.

CARDIOLOGY RPM

Arrhythmia, AF, palpitations - continuous monitoring where a single resting ECG cannot detect paroxysmal events 

DIABETES CAN

Cardiac autonomic neuropathy (CAN) monitoring for patients with Type 2 diabetes - a clinically silent condition until advanced

NEPHROLOGY DIALYSIS

Cardiac monitoring across dialysis sessions where fluid shifts and electrolyte changes affect heart rhythm

CARDIO-ONCOLOGY

Monitoring for patients on cardiotoxic drug regimens including ibrutinib, ADT, and anthracyclines

PSYCHIATRY QTC

QTc monitoring for patients on clozapine, SGAs, and ADHD stimulants - closing the prescriber surveillance gap at point of care

GENERAL PRACTICE

GP-initiated one-minute workflow for palpitations, pre-referral assessment, and cardiac risk screening at consultation

Specialist Diagnostic Channels

Cardiologist

Oncologist

Endocrinologist

Nephrologist

Psychiatrist

The table below shows examples of cardiac monitoring shortfalls across five specialties. ecgme® and the mapdx™ system are designed to make context aware ECG monitoring more accessible for patients both in the clinic and at home.

Specialist Area
Diagnostic Shortfalls
Remote Patient Monitoring (Cardiology)
Holter monitor runs 24–48 hrs. Paroxysmal arrhythmias are often not found in the short diagnostic window of Holter monitoring. No longitudinal assessment of ECG or contextual analysis with concurrent medications or comorbidities.
Diabetes / CAN
Cardiac autonomic neuropathy (CAN) is clinically silent until advanced. Heart rhythm segment intervals and HRV are affected by glycemic control and insulin regimen. No standard monitoring captures all concurrently.
Dialysis / Renal
HD patients undergo 2.2M sessions/yr in Australia. Intradialytic cardiac events go unmonitored. Fluid shifts, electrolyte changes, and EPO affect cardiac rhythm.
Cardio-Oncology
Ibrutinib, ADT, and anthracyclines carry direct cardiotoxicity risk. Oncology teams monitor tumour response; cardiac monitoring is episodic and not linked to treatment sequencing, drug cycles or cumulative dose.
Psychotropic / QTc + ADHD
Clozapine, SGAs, and ADHD stimulants carry QTc prolongation and arrhythmia risk. GP prescribes the drug; cardiac monitoring is rarely triggered. 52% of scripts written by GPs with no cardiology link.

Case Studies

Positive impact being made with ecgme® in clinical use, and BiosignalsDx is delighted to share the following two cases of actual patients under management of Cardiologist A/Prof. Stephan Foy. 

Lynn, a 64 year old woman has episodes of palpitations that she describes as her “heart missing a beat”. These are intermittent and most often noticeable at night. The episodes can continue for many hours. She often has an elevated heart rate during these episodes. It seems to precipitate a cough. The episodes result in anxiety about her heart health. She was advised that ECG showed ectopic beats, but with her more frequent and prolonged episodes she has never had ECG confirmation of the episodes. I recommended she acquire an ecgme device from www.biosigdx.com to provide her with the confidence of recording her heart rhythm, so as to provide herself with reassurance. Some months later, she returned to see me with multiple recordings on her “ecgme” device that show atrial and ventricular ectopic beats during her episodes of palpitations. One recording shows a sinus pause of a few seconds duration. We discussed the benign nature of her ectopic beats, which she feels will go a long way to reducing her anxiety. She was advised that asymptomatic and infrequent brief pauses are of no immediate concern, but if these become longer or symptomatic, she will require permanent pacemaker.

Phil, 73 year old man has been experiencing infrequent palpitations that were more frequent during the colder months. He does not have any untoward symptoms during palpitation episodes; no dizziness, no black out. I spoke with him in October about recording his ECG during an episode and advised that he obtain a TGA approved hand held ECG event monitor (ecgme) from www.biosigdx.com. He has had one episode of palpitation since obtaining his ecgme device and recorded the event in December. The PDF of 30s recording was sent to me as a text message; it confirms atrial fibrillation. He was commenced on an anticoagulant to reduce his risk of stroke due to paroxysmal atrial fibrillation. He contacted me 3 months later, thanking me for the “health confidence” that he has gained with a confirmed diagnosis and appropriate treatment. He stated that he had just completed his longest ocean swim, 3.8km; the event is now an annual family tradition. The company appreciates Stephan sharing these two examples of how ecgme® is making a difference in clinical care.

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